helminth

Researchers have now determined the activation status of human neutrophils from patients with acute and chronic infections of T. gondii using flow cytometry.

Takaki et al., used a S.mansoni Zebrafish infection model and confocal microscopy demonstrated that only mature S.mansoni eggs induce granuloma formation, while immature eggs have limited capacity to do so.…

9th November 2018 Filbey et al., aimed to determine how chronic Heligmosomoides polygyrus (Hp) gastrointestinal infection can influence systemic and localised immunity against other helminth infections.

Interesting work by Chan and colleagues describes an unknown mechanism of action of the tetracyclic tetrahydroisoquinoline praziquantel (PZQ) the drug ...

29th September, 2017T helper (Th) 2 cells have been shown to be important in protection against Schistosoma mansoni while increasing susceptibility to Leishmania major. Researchers...

27th September, 2017Type I interferons (IFN) have been traditionally associated with innate immune defences against viruses and bacteria which ultimately result in Th1/17-type...

28th July, 2017Type 2 immunity is broadly associated with cellular and cytokine response for interleukin (IL) production, including IL-4, IL-5, and IL-13, of the Th2 phenotype. The Type 2...

23rd November, 2016Chronic helminth infections have been associated with immunological hyporesponsiveness. This favours the survival of the helminths...

12th October, 2016Despite eradication attempts, up to 2 billion people in developing countries have chronic helminth infections.

12th September, 2016Targeting IL-4 receptor alpha mediated signalling: A new therapeutic strategy for fibroproliferative diseases? Schistosomiasis is a parasitic disease caused by infective helminthes of the trematoda class. It is