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What is your name?
Sohail Hassan Mahmood
What is your current position?
Director & CEO, Living In Silico Inc.
Which institute and country do you work in?
Sheridan College, Canada
What is your home country?
Canada
What are your research interests?
Simulations, drug discovery, ILCs
Tell us about yourself and your research interests:
We (Living in Silico Inc.) are interested in determining novel drugs using protein-protein simulation. We are building an immunological identity with drug production that allows for specific immunotherapies based on specific immune cell behaviour in disease states. One aspect would be polarization of cells, based on various stimuli, innate immune cells can orchestrate later adaptive responses. If a specific APC becomes differentiated to prevent influx of cells it would be anti-inflammatory and if promoting inflammation it would be inflammatory.
We would like to extend the idea further of APC polarization and the behavioural changes leading to massive changes in immune responses to alter responses to stimuli such as in tumour microenvironment where vascular changes diminishing can lead to tumour size decreases. We hope to achieve these goals by understanding the mechanisms of the microenvironment to maintain growth and cancerous growth and target specific behaviours rather than general chemo and immunotherapies.
What are your online profiles?
LinkedIn: Sohail Hassan Mahmood
Immunology Keywords: Immunotherapies, Simulations, ILCs
