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What is your name?
Jennifer Enciso García
What is your current position?
PhD Student, Biochemical Sciences
Which institute and country do you work in?
CIBIOR, Mexican Institute for Social Security, National Autonomous University of Mexico (UNAM), Mexico City, Mexico
What is your home country?
Mexico
What are your research interests?
Systems Immunology, Acute lymphoblastc leukemia, Tumor microenvironment
Tell us about yourself and your research interests:
I received my B.Sc. and M.Sc. from the National Autonomous University of Mexico in 2013 and 2015. I am currently pursuing my Ph.D in Biochemistry with a focus in systems biology applied on hematological diseases, more specifically acute lymphoblastic leukemia (ALL). Since my Masters project I’ve been working in the development of a computational discrete model representing some of the main intercellular communication pathways between hematopoietic primitive cells and the bone marrow niche cells in order to understand how they are involved in leukemia maintenance and progression. I am dedicated to the study of bone marrow microenvironment remodelation in ALL towards a proinflammatory state and its participation in the establishment of feedback loops among different sub-systems (eg. Inflammatory cues, stromal cells, leukemic cells and normal hematopoietic cells). The pro-inflammatory microenvironment may be the key factor which “tilt the balance” in the competition between normal and cancer cell populations in the leukemic bone marrow. On the other hand, through the discrete model I also want to probe the hypothesis about the role of inflammatory hits in the initial stages of B-ALL development perturbing the proliferation-differentiation balance.
What are your online profiles?
LinkedIn – Jennifer Enciso Garcia
ResearchGate – Jennifer Enciso
Immunology Keywords: Cytokines, TLRs, RAG
