https://new.immunopaedia.com/wp-content/uploads/2021/03/Photo-Jasmin-Knopf-scaled.jpg
What is your name?
Jasmin Knopf
What is your current position?
Post-doctoral fellow
Which institute and country do you work in?
Department of Medicine 3, Universitätsklinikum Erlangen, Germany Director: Prof. Dr. Georg Schett, Germany
What is your home country?
Germany
What are your research interests?
Neutrophil biology, Neutrophil Extracellular Traps (NETs), Antibody glycosylation
Tell us about yourself and your research interests:
My background is non-academic and I was the first in my family to study at a university. I studied Molecular Medicine and since the beginning, I was interested in biology and the immune system in particular, in a more clinical setting. Therefore, I became a scientist in the field of Rheumatology and Immunology. I’m especially interested in the role of Neutrophil extracellular traps (NETs) in autoimmune and chronic inflammatory diseases, such as Systemic Lupus Erythematosus or Rheumatoid Arthritis. Currently, I focus on the composition and degradation mechanisms of NETs and how they can change the effector functions of antibodies and other proteins, e.g. by the modification of cellular glycosylation. Additionally, I’m researching the role of NETs in COVID-19. There is evidence that NETs and NET-derived proteins are not only responsible for thrombus formation in these patients but also might modify the spike protein. Finding a way to treat or even prevent vascular occlusions by NETs may also be applicable to other diseases with vasculopathies (as e.g. described for Malaria).
Furthermore, I want to help educate and guide young people, and promote research opportunities for students from all over the world.
What are your online profiles?
Linkedin, ResearchGate
Imunology Keywords:
Neutrophils, Neutrophil Extracellular Traps (NETs), COVID-19
