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My name is Maryam Sadat Seyedmehdi, and I am a recent master’s graduate in genetics. My journey into science began early in childhood, inspired by my father, a medical doctor and pathologist. Wandering around his lab, I was fascinated by the microscope and the mysterious world it revealed. Long story short, I chose Medical Laboratory Sciences for my bachelor’s degree, as a foundation in diagnostic science. Later on, my interest narrowed toward Genetics, which became the focus of my master’s studies. During this time, I became drawn to immunogenetics—a field that sits at the crossroads of genetics, immune science, clinical medicine, and computational biology.
We would love to hear more about your ongoing research. What projects are you currently working on, and how do they impact the field?
My latest work with Dr. Shirin Farivar focuses on identifying gene expression signatures and biomarkers of IDH-mutant gliomas, using transcriptomic datasets and integrative bioinformatics approaches. We tried to explore how tools like gene expression profiling and immune cell estimation can enhance early diagnosis. The goal was to better understand the molecular landscape of these tumours and potentially contribute to more personalised diagnostic or therapeutic strategies.
In parallel, I am also involved in collaborative efforts with Prof. Zahra Chavoshzadeh’s research group, a true gem in the field of IEIs in Iran at Mofid Children’s Hospital– a referral centre for Inborn Errors of Immunity. I’m engaged in ongoing studies on Leukocyte Adhesion Deficiencies (LADs), Congenital Disorders of Glycosylation (CDGs), and Combined Immunodeficiencies (CIDs). We also gather patient information to support registry activities and help build the infrastructure needed for future policy-making, research, and clinical decisions.
Please tell us about your work in gender equality in science in Iran?
The story of Gender Equality in Sciences began with a call for ideas from IUIS. After receiving a grant, a group was formed, which I later joined as part of the main team. Since then, I’ve been involved in several initiatives to support women in science in Iran. Over the past two years, we launched our own podcast and organized Women in Science Day events, with the support of Dr Mehrnaz Mesdagho. These events aim to celebrate the achievements of women scientists in Iran and promote equity and mentorship across generations. Our goal is to help women and girls recognise their strengths and believe in their potential. Our message is simple: there are no limits to how far you can go. With hard work, curiosity, and teamwork, growth will come. We want to build a space where women feel heard, can succeed, and lift others as they rise.
What inspired you to choose immunology as your focus within the field of science? Has this evolved over time?
My interest in immunology grew gradually, as I began to see how central the immune system is to many diseases. At the same time, my sister, Marjan, was studying immunology, and through her, I connected with people in the field. Interestingly, many of their discussions often circled back to genetics, which made me realize how closely the two areas are linked. Those conversations opened my eyes to the depth and impact of both fields and made it clear to me that this was the direction I wanted to pursue.
What specifically stood out about Immunopaedia that made you want to become an ambassador, and how has your experience as an ambassador affected you?
Being an Immunopaedia ambassador has given me the opportunity to connect with people who share the same passion—people from my scientific “tribe.”
Through this role, I’ve also had the opportunity to interview inspiring individuals, learn about their journeys, and hear their advice and experiences. It’s been a source of both motivation and growth, and I’m grateful for the platform Immunopaedia provides to young scientists like me.
Based on your own experience, what one piece of advice would you give someone who wants to study or research immunology?
My advice would be to embrace teamwork, stay curious, and be open to interdisciplinary approaches. Immunology today is closely linked with fields like data science, genomics, and artificial intelligence. Don’t hesitate to learn coding, explore databases, or connect with international communities. Also, focus on building a strong network and be patient—finding your niche takes time, but it’s definitely worth the effort.
Can you share a moment of unexpected joy or surprise in your scientific career over the past three years that has stayed with you?
As an early career professional and new to the field, last autumn I had the opportunity to attend ESID2024 in Marseille, France– a true highlight! It was incredibly inspiring to be surrounded by experts I’ve long admired. Meeting scientists like Prof. Luigi Notarangelo, Prof. Bodo Grimbacher, and Prof. Klaus Warnatz—whose names I had only seen on papers before—was a pleasure, a source of inspiration and a real honour.
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