September 2025

New research shows that cutting off blood flow prematurely ages the immune system, creating a cancer-tolerant state that accelerates tumour growth (Figure 1). Figure 1: Graphical abstract. Ischemia, caused by…

Medical radiation exposure has doubled over the past decade, largely due to diagnostic tools such as X-rays and CT scans. While often lifesaving, radiation weakens the immune system by depleting…

A major Swedish study has shown that diet plays a critical role in how chronic diseases build up over time in older adults. Researchers more than 2,400 older adults in…

TH17 cells, known for secreting IL-17, play a role in host defence and inflammation. While conventional TH17 cells arise in the periphery, recent work identified a population of natural TH17…

Researchers have uncovered a key role for the complement system in driving inflammation that leads to preterm birth and fetal brain injury (Figure 1). The findings highlight complement as a…

Researchers have developed an antibody-based therapy that could transform how influenza is treated and prevented (Figure 1). In a study the team demonstrated that a cocktail of three antibodies protected…

A team of researchers have discovered that applying electrical stimulation to macrophages, key immune cells involved in defence, repair, and inflammation, can reprogram them into an anti-inflammatory, pro-healing state (Figure…

Our brains can trigger immune defences at the mere sight of someone who appears sick, even without direct exposure to pathogens. A new study demonstrates that visual cues of illness…

The tumour microenvironment (TME) is not just made up of cancer cells, it’s a dynamic ecosystem of immune cells, stromal cells, blood vessels, and signalling molecules, all constantly reshaping as…

In a new study researchers introduce T-CellAnnoTator (TCAT), a computational pipeline designed to make sense of this complexity by quantifying gene expression programs (GEPs) across millions of single cells...

T cells are central to the immune system, mounting specialized responses that include killing infected cells, releasing cytokines, or driving inflammation. Traditionally, immunologists have described T cell function in terms…

New research shows that lowering IL-6 activity may help prevent cardiovascular disease, without leaving people more vulnerable to infections...