May 2025

Idiopathic Interstitial Pneumonia (IIP) is a complex group of lung diseases without a known cause, often resulting in progressive lung fibrosis. Unlike interstitial lung disease (ILD) associated with connective tissue…

In an unexpected twist, researchers are exploring how a virus known for causing disease might be repurposed to help fight cancer. Specifically, a herpesvirus that naturally infects squirrel monkeys is…

In a surprising twist to our understanding of thymic education, a recent study from the Tak Wak lab in Toronto, Canada, unveils a non-neuronal role for acetylcholine (ACh) in shaping…

A new study reveals a potential link between maternal selenium levels during pregnancy and reduced risk of streptococcal infections in children (Table 1). The findings suggest selenium’s key role in…

A new study reveals the diverse immune landscapes of bone metastases using RNA sequencing (Figure 1). By analysing samples from eight different cancer types, the team identified three distinct immune…

Differentiating tuberculous pleural effusion (TPE) from para-pneumonic pleural effusion (PPE) is challenging due to overlapping clinical signs. Conventional diagnostic methods, such as adenosine deaminase levels, can misclassify cases. This study…

Community-acquired pneumonia (CAP) varies widely in clinical presentation and patient outcomes, highlighting the need for improved stratification methods. Traditional clinical scoring systems have limited accuracy for predicting severe cases and…

A new study provides important insights into how the highly effective YF17D yellow fever vaccine activates the human immune system—offering valuable clues for designing new, fast-acting vaccines (Figure 1). The…

Coeliac disease is an autoimmune disorder where ingestion of gluten damages the small intestine. While most patients improve with diet modification, ~1% develop refractory coeliac disease, which does not respond…

Immune checkpoint inhibitors (CPIs) have revolutionized cancer treatment, enabling the immune system to better target tumours. However, they can lead to immune-related adverse events (irAEs), including CPI-induced diabetes mellitus (CPI-DM).…

As people with multiple sclerosis (MS) live longer, healthcare providers face new challenges in treating elderly patients. The treatment of elderly individuals with MS is complicated by the effects of…