January 2024

While most individuals infected with the SARS-CoV-2 virus recover from the acute illness, a notable subset experience prolonged symptoms referred to as Long Covid, which present a diverse range of…

Lung resident alveolar macrophages (AMs) are the first immune cells that Mycobacterium tuberculosis (M.tb) encounter in the lungs, and play a protective role in the host’s ability to defend itself…

Individuals afflicted with Guillain-Barré syndrome (GBS) have a rare and varied peripheral nervous system disorder, often triggered by previous infections, resulting in severe muscle weakness. In severe cases, respiratory muscle…

A key player in the cytokine storm is Interleukin-6 (IL-6), which contributes to inflammation and tissue damage. IL-6 exerts its effects by binding to IL-6 receptors on cells, instructing them…

Amyotrophic lateral sclerosis (ALS) is characterized by the degeneration of upper motor neurons in the brain and lower motor neurons extending from the spinal cord to muscles. A recent study…

In a recent study, researchers uncovered a significant role played by beneficial commensal microbes in the gut: they stimulate the host to produce T cells that contribute to gut health…

In a recent study, researchers investigate immune cell behavior during human lung development in embryos and fetuses (Figure 1). While previous research has extensively covered immune cell functions in various…

Mutations in the p53 tumor suppressor gene not only drive the growth of cancer cells but also impact the microenvironment surrounding tumours. Recent research reveals that breast cancer cells with…

In a recent study, researchers described the multifaceted roles of JAK inhibitors in inflammation, shedding light on the need for a more pragmatic approach in their application across varying types…

In the pursuit of safeguarding populations against infections, vaccine development stands as a critical endeavour. Recent strides in this field have spotlighted epitopes—short protein fragments of pathogens—as a novel approach…