August 2021

breaking news

Reprogramming the Tumour Microenvironment – Improving Cancer Survival

Through the use of single-cell transcriptome, proteome, and immune cell analysis of the tumour microenvironment (TME), Hicks, et al., were able to show that that combination therapy elicits significant and…

ChelekaAugust 31, 2021

breaking news

Does B.1.351 SARS-CoV-2 variant escape T cell immune responses?

In a recent preprint, Riou and colleagues aimed to provide an overall measure of immune evasion by assessing neutralizing antibody and T cell responses in 44 South African COVID-19 patients…

ChelekaAugust 26, 2021

breaking news

Neutrophil dominance leads to protection from P. falciparum blood-stage merozoites

In an interesting study, researchers showed that neutrophils contribute significantly to IgG-mediated phagocytosis of blood-stage P. falciparum merozoites and protection against febrile malaria. These findings further elucidate neutrophil antibody-mediated immune…

ChelekaAugust 20, 2021

breaking news

A novel pathway of immune and host cell evasion by Mycobacterium tuberculosis

Researchers from the University of Maryland and the US National Institutes of Health have discovered a novel pathway of host cell manipulation and innate immune evasion by Mtb. They have…

ChelekaAugust 18, 2021

breaking news

Pre-clinical evaluation of a vaccine that induces both SARS-Cov-2 and yellow fever virus immunity.

Researcher aimed to develop a candidate SARS-Cov-2 vaccine that uses the YF17D vaccine as a vector to express a non-cleavable pre-fusion form of the SARS-CoV-2 spike antigen (YF-S0).

ChelekaAugust 16, 2021

breaking news

Can neutrophils adopt antigen-presenting cell functions, and if so how?

We highlight recent research that investigated whether neutrophil conversion to neutrophil antigen presenting cells (nAPCs) requires the engagement of their Fcγ receptor, as well as exploration of the therapeutic potential…

ChelekaAugust 11, 2021

breaking news

IUIS Webinar: HIV prevention- antibodies and vaccine development (part 2)

6 August 2021 Prof Lynn Morris presented results from the antibody-mediated prevention trial that tested the ability of VRC01 broadly neutralising Ab(specific for the HIV envelope protein CD4 binding site…

ChelekaAugust 6, 2021

breaking news

IUIS Webinar: HIV prevention- antibodies and vaccine development (part 1)

5 August 2021 Prof. Lynn Morris began her talk comparing the HIV and SARS-Cov-2 epidemics, at the peak of the HIV epidemic approximately annual mortality was 1.8 million deaths reported…

ChelekaAugust 5, 2021

breaking news

Potent neutralising antibodies against SARS-CoV-2 variants of concern.

2 August 2021 Wang and colleagues aimed to isolate potent neutralising antibodies that have activity against VOCs as well as other SARS-Cov-2 variants, as well as determine whether these potent…

ChelekaAugust 2, 2021

Reprogramming the Tumour Microenvironment – Improving Cancer Survival

Does B.1.351 SARS-CoV-2 variant escape T cell immune responses?

Neutrophil dominance leads to protection from P. falciparum blood-stage merozoites

A novel pathway of immune and host cell evasion by Mycobacterium tuberculosis

Pre-clinical evaluation of a vaccine that induces both SARS-Cov-2 and yellow fever virus immunity.

Can neutrophils adopt antigen-presenting cell functions, and if so how?

IUIS Webinar: HIV prevention- antibodies and vaccine development (part 2)

IUIS Webinar: HIV prevention- antibodies and vaccine development (part 1)

Potent neutralising antibodies against SARS-CoV-2 variants of concern.

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