April 2021

Aged Neutrophils support tumor metastasis

Since nothing is known about aged neutrophils in cancer biology and mature neutrophils in the circulation are considered to be heterogenous, Peng et al. examined how metastatic cancers regulate mature…

ChelekaApril 28, 2021

breaking news

P.falciparum secretes extracellular vesicles with functional 20S proteasomes to prime RBCs for parasite invasion

P.falciparum is able to modulate the RBC’s membrane stiffness. However, can P.falciparum remodel naïve surrounding RBCs in preparation for invasion while growing inside their host RBC?

ChelekaApril 26, 2021

breaking news

Pregnant women show elevated levels of anti-inflammatory glycosylation patterns of IgG antibodies

Damelang et al. investigated the ability of IgG antibodies, specific to DBL2 and DBL3 (two VAR2CSA domains), of pregnant women from a malaria-endemic area to activate human primary NK cells…

ChelekaApril 23, 2021

breaking news

First report on Effectiveness of HPV Vaccination in LMICs – Rwanda and Bhutan

HPV infection is attributable to about 99.7% of cervical cancer cases globally in addition to other anogenital and oropharyngeal cancers. Researchers have recently published data from Rwanda and Bhutan that…

ChelekaApril 20, 2021

breaking news

Does ACE2 expression & cytotoxic lymphocyte levels indicate a risk factor for COVID-19?

Article in the American Society of Microbiology outlined how differences in expression within lung tissue may impact the effect of SARS-CoV-2 infection on the individual.

ChelekaApril 16, 2021

breaking news

Immunopathogenesis of Autoimmune Hepatitis

Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease that occurs at any age and mainly affects women. Understanding the immunopathogenesis of AIH is crucial for the development of treatment…

ChelekaApril 13, 2021

breaking news

B1.351 (501Y.V2) induces cross-reactive Ab responses to other SARS-CoV-2 variants.

Moyo-Gwete et al., 2021 demonstrated that 501Y.V2 elicits robust neutralizing antibody responses against both the original variant and 501Y.V3 (P.1), which indicates high levels of cross-reactivity. Watch video summary for..

ChelekaApril 9, 2021

breaking news

IUIS-Immunopaedia-Frontiers Webinar on Immunology taught by P. falciparum

Using a systematic search for antibodies that bind broadly to infected erythrocytes, they discovered a new class of Abs generated by insertions of genomic DNA encoding human inhibitory receptors (LAIR1)…

ChelekaApril 7, 2021

breaking news

Is tumour circulating DNA a better tool for cancer diagnostic and prognostic than immunological biomarkers?

Although head and neck squamous cell carcinomas (HNSCCs) is the seventh most frequent type of cancer, they both still have no validated biomarkers and lack specific therapies.

ChelekaApril 1, 2021

Aged Neutrophils support tumor metastasis

P.falciparum secretes extracellular vesicles with functional 20S proteasomes to prime RBCs for parasite invasion

Pregnant women show elevated levels of anti-inflammatory glycosylation patterns of IgG antibodies

First report on Effectiveness of HPV Vaccination in LMICs – Rwanda and Bhutan

Does ACE2 expression & cytotoxic lymphocyte levels indicate a risk factor for COVID-19?

Immunopathogenesis of Autoimmune Hepatitis

B1.351 (501Y.V2) induces cross-reactive Ab responses to other SARS-CoV-2 variants.

IUIS-Immunopaedia-Frontiers Webinar on Immunology taught by P. falciparum

Is tumour circulating DNA a better tool for cancer diagnostic and prognostic than immunological biomarkers?

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