March 2020

Biological factors that determine susceptibility to SARS-CoV-2 and severity of COVID-19 are yet to be fully understood. A pre-print released in medRxiv by Zhao et al suggests that the ABO…

Retrospective analysis of COVID-19 patient history showed that 12-22% and 23-30% of severe COVID-19 patients also had diabetes and hypertension, respectively. This and other reports suggest that hypertension and diabetes…

Andersen et al have described the genomic structure of SARS-CoV-2. Notably, the virus has a receptor binding domain consisting of 6 amino acids which not only differentiates it from SARS-CoV…

Since the SARS-CoV-2 virus started to circulate in the different countries that the COVID-19 pandemic has reached, a possible seasonal pattern in the presentation of the disease has been hypothesized.…

27 MarchSheahan et al recently pre-published a paper that states that ribonucleoside analog β-D-N4-hydroxycytidine (NHC, EIDD-1931) has broad spectrum antiviral activity against SARS-CoV 2, MERS-CoV, SARS-CoV, and related zoonotic group…

Lin et al., 2020 have described a hypothetical model of SARS-CoV-2 pathogenesis based on the immune response against SARS, MERS and influenza infection. In all cases, lymphopenia accompanied by the…

Mehat, P. et al recently stated that there is accumulating evidence suggests that a subgroup of patients with severe COVID-19 might have cytokine storm syndrome. Immunosuppression treatment could help severe…

We report findings of an Australian COVID-19 Case study of a 47 year womanThevarajan et al., aimed to determine the “kinetics and breadth of immune responses associated with clinical resolution…

A recent study by Liao et al., “comprehensively characterised the lung immune microenvironment of bronchoalveolar lavage fluid (BALF) from 3 severe and 3 mild COVID-19 patients and 8 previously reported…