August 2019

Can vaccinating cats against their own proteins reduce cat allergies in humans?

European Researchers collaborated to develop a new strategy to treat cat allergies in human subjects by immunizing cats against their own major allergen. The vaccine targeting Fel d1 in cats…

ChelekaAugust 30, 2019

Cross-section through liposome. Water-attracting ends of molecules (white); Water-repellent ends (brown). Source: Wikimedia Commons, Author Philcha)

breaking news

Use of future liposomal cancer oncology treatment

27August Researchers in South Korea have identified a new method for treating difficult cancers using state-of-the art liposome technology. The purpose of the study was to demonstrate the utility of…

ChelekaAugust 27, 2019

breaking news

What other disease affect individuals with olive pollen allergies?

Sabour Alaoui et al., found that 30.25% of the people surveyed in Béni Mellal, Morocco have a olive pollen allergy, this is within range of the prevalence found in urban…

ChelekaAugust 23, 2019

The different immune-related roles of osteoclasts. Beyond bone resorption, osteoclasts share many functions with their progenitors including phagocytosis, antigen presentation and immunomodulation. (Source Madel et al. 2019)

breaking news

The Immune Function of Osteoclasts

Osteoclasts (OCLs) are multi-nucleated phagocytes of monocytic origin that are responsible for bone resorption. Changes in their bone resorption function are associated with various pathologies such as osteoporosis, chronic inflammation…

ChelekaAugust 21, 2019

Dengue Infographic Source: http://www.searo.who.int/entity/vector_borne_tropical_diseases/topics/dengue/Dengue.pdf?ua=1

breaking news

TAK-003 induces functional DENV cross-reactive cellular immmunity

A study by Waickman et al., aimed to investigate T cell responses induced by TAK-003. They showed that TAK-003 induces strong CD8 T cells (IFN-γ+CD107+) responses that last for at…

ChelekaAugust 19, 2019

"Wildling mice: A new preclinical tool to study human disease Wildling mice combine the low genetic diversity of inbred laboratory mice with a wild mouse microbiota harboring bacteria, fungi, and viruses. This generates a more translationally relevant animal model of human disease for studying host-microbiota interactions, as well as for predicting the outcomes of human clinical trials." Source Nobs & Elinav Science 2019)

breaking news

Wild is better: in-bred mice born to wild mice resemble human responses

Low microbial diversity of laboratory (lab)-mice is suggested to be one of the main contributors to the discrepancy between lab-mice and humans. Rosshart et al., thus developed a wildling mouse…

ChelekaAugust 14, 2019

Life cycle image and information courtesy of DPDx (CDC’s Division of Parasitic Diseases and Malaria (DPDM))

breaking news

Do NK cells play an important role in anti-Trypanosomiasis immunity?

Trypanosomiasis poses a serious threat to the agricultural economy. Treatment of the disease has severe side effects and currently no vaccine exists. Onyilagha et al., aimed to determine if NK…

ChelekaAugust 7, 2019

Properties and relationship of the main MAIT cell subsets. (Source: Dias et al., 2018 PNAS)

breaking news

Are MAIT cells detectable in lymph?

It is unclear whether depletion of MAIT cells in the blood is due to apoptosis or migration to sites of infection, and whether MAIT cells in blood and tissue have…

ChelekaAugust 2, 2019

Young women and children carrying out their daily activities in Lake Victoria, an area endemic for Schistosoma mansoni. Bugonga, Wakiso District, Uganda (Photo by S. Yegorov).

breaking news

Does S. mansoni treatment affect HIV susceptibility?

Yegorov et al., employed ex vivo HIV entry assays in combination with flow cytometry, cytokine measurements and transcriptome analysis to gain insight on how standard praziquantel schistosomiasis therapy affects systemic…

ChelekaAugust 1, 2019

Can vaccinating cats against their own proteins reduce cat allergies in humans?

Use of future liposomal cancer oncology treatment

What other disease affect individuals with olive pollen allergies?

The Immune Function of Osteoclasts

TAK-003 induces functional DENV cross-reactive cellular immmunity

Wild is better: in-bred mice born to wild mice resemble human responses

Do NK cells play an important role in anti-Trypanosomiasis immunity?

Are MAIT cells detectable in lymph?

Does S. mansoni treatment affect HIV susceptibility?

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