July 2018

Can profiling CD8 T cell responses from Ebola Survivors improve vaccine design?

31st July 2018 The role of CD8 T cells in protective vaccine induced responses against ebola virus is not clearly defined.

ChelekaJuly 31, 2018

Koh et al., 2018 Fig 3I: Micrographs showing a PF4+TUNEL+ P. knowlesi infected cell after platelet treatment. Scale bars = 5 μm. Images were taken at 630x magnification on an Axio Observer inverted fluorescence microscope coupled to an Axiocam 503 monochrome camera with ZEN 2 software (Carl Zeiss, Germany). Bars indicate means of replicate data points. Abbreviation: DIC, differential interference contrast.

breaking news

Can platelets directly kill Plasmodium sp. ?

27th July 2018 Studies have shown that platelets can bind and kill infected P.falciparum-infected RBCs (iRBC) and platelet depletion ...

ChelekaJuly 27, 2018

Source: Pinheiro et al., 2018 (PloS Neg. Dis): Proposed model for L6 lineage (red) dominant circulation without L1 lineage replacement (blue) in the SJRP population, with the main differences found between the two DENV-1 lineages.

breaking news

Can viral Immunogenicity govern DENV epidemiological fitness ?

24th July 2018 This study demonstrated the interplay between viral replicative, immunological and epidemiological

ChelekaJuly 24, 2018

breaking news

How do tuft cells induce Type 2 Responses?

20th July 2018 A study conduted by Nadjsombati et al., aimed to determine how tuft cells are activated in the small intestines.Transcriptional profiling revealed that the ..

ChelekaJuly 20, 2018

breaking news

CD32: marker of HIV reservoir?

17th July 2018 A study published by Descours et al., in Nature last year, identified CD32a as marker of the CD4 T cell HIV reservoir. This study showed that CD32a+…

ChelekaJuly 17, 2018

breaking news

New Hope for TB Vaccines

13th July 2018 Tuberculosis (TB) is the leading cause of death due to infectious diseases worldwide. One of the approaches to end the TB epidemic is the development of efficacious…

ChelekaJuly 13, 2018

breaking news

HIV vaccine induces similar responses in humans and rhesus macaques.

10th July 2018 One of the major challenges of developing a vaccine against HIV, is the extensive HIV strain diversity. One approach being ...

ChelekaJuly 10, 2018

Ben Youssef et al., 2018 JEM. (B) Parallel changes in the CD45RO and CD8β Vα7.2+ CD161high cell phenotype during the first 12 mo after UCB transplantation. Results show the mean frequencies ± SEM of CD45RO− and CD8β+ cells at the different time points. The rebound in CD45RO− MAIT numbers around 9 mo after HSCT (P = 0.06 compared with val- ues at 6 mo) coincides with the emergence of newly thymus-derived naive cells.

breaking news

6th July 2018 Researchers from France, aimed to determine the postnatal expansion and maturation of MAITs from birth to adulthood using cross-sectional samples. Ben Youssef et al., predominantly defined MAITs as…

ChelekaJuly 6, 2018

breaking news

Public Antibody Clonotypes observed in HIV+ individuals.

3rd July 2018 A collaborative research project between researchers in South Africa and US, examined the antibody repertoire in HIV ...

ChelekaJuly 3, 2018

Can profiling CD8 T cell responses from Ebola Survivors improve vaccine design?

Can platelets directly kill Plasmodium sp. ?

Can viral Immunogenicity govern DENV epidemiological fitness ?

How do tuft cells induce Type 2 Responses?

CD32: marker of HIV reservoir?

New Hope for TB Vaccines

HIV vaccine induces similar responses in humans and rhesus macaques.

Ontogeny of MAITs

Public Antibody Clonotypes observed in HIV+ individuals.

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